Prudence Lifecare Pvt. Ltd.
(R)-3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate
Manufactured and supplied from our WHO-GMP, GLP and ISO 9001:2015 certified facility in Ankleshwar, Gujarat, India. This is the key chiral aminopropyl-indoline intermediate used to manufacture Silodosin, a selective α1A-adrenoceptor antagonist.
- CAS Number
- 239463-72-0
- Molecular Weight
- 363.45 g/mol
- Product Type
- API Intermediate
- Used to Manufacture
- Silodosin
What is this intermediate?
(R)-3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate — also known as 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile — is the key chiral aminopropyl-indoline building block used in the industrial synthesis of Silodosin. Its free primary amine is condensed with 2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl methanesulfonate — another intermediate manufactured by Prudence Lifecare — to build Silodosin's full molecular skeleton, which is then deprotected and hydrolyzed to give the finished API.
Application
- Silodosin synthesis intermediate
- Alpha-1A adrenoceptor antagonist API manufacturing
- Custom synthesis & CDMO supply
- Pharmaceutical research & QC reference
Chemical & technical data
Full verified identifiers for this intermediate, cross-checked against supplier reference data.
| Product Name | (R)-3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate |
|---|---|
| CAS Number | 239463-72-0 |
| Molecular Formula | C22H25N3O2 |
| Molecular Weight | 363.45 g/mol |
| Exact Mass | 363.1947 |
| Systematic Name | 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile |
| InChIKey | SPIYQPPDQNLNDT-MRXNPFEDSA-N |
| Product Type | Active Pharmaceutical Ingredient (API) intermediate |
| Downstream API | Silodosin (CAS 160970-54-7) |
Specification, purity grade, packaging and Certificate of Analysis details available on request.
Manufacturing & supply
Prudence Lifecare Pvt. Ltd., Unit-II of Prudence Pharma Chem (established 2003), is a WHO, GMP, GLP and ISO 9001:2015 certified Active Pharmaceutical Ingredient and intermediates manufacturer based in GIDC Ankleshwar, Gujarat, India. This intermediate is manufactured under the same quality systems that govern our full API and intermediates portfolio, supplying formulation companies, API manufacturers and contract manufacturers across India and exporting to Asia, Europe, Africa and the Middle East.
Quality, certifications & documentation
- WHO-GMP, GLP, ISO 9001:2015 and ISO 14001 certified facility
- Certificate of Analysis (CoA) available on request
- Custom purity/particle-size specifications available on request
Why choose Prudence Lifecare
- WHO, GMP, GLP and ISO-certified facility in Ankleshwar, Gujarat, India
- In-house manufacture of both major Silodosin synthesis intermediates
- Also the manufacturer of the finished Silodosin API
- Export experience across Asia, Europe, Africa and the Middle East
- Custom synthesis and contract manufacturing (CDMO) capability
Frequently asked questions
What is (R)-3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate used for?
It is the key chiral aminopropyl-indoline intermediate used in the industrial synthesis of Silodosin, a selective α1A-adrenoceptor antagonist.
What is the CAS number of this intermediate?
239463-72-0.
What is the molecular formula of this intermediate?
C22H25N3O2.
What is the molecular weight of this intermediate?
363.45 g/mol.
Who manufactures this intermediate in India?
Prudence Lifecare Pvt. Ltd. manufactures this intermediate at its WHO-GMP certified facility in Ankleshwar, Gujarat, India.
What does this intermediate react with to form Silodosin?
Its free amine reacts with 2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl methanesulfonate — also manufactured by Prudence Lifecare — followed by deprotection and hydrolysis to yield Silodosin.
Does Prudence Lifecare also manufacture the finished Silodosin API?
Yes, Prudence Lifecare manufactures Silodosin (CAS 160970-54-7) to IP and IHS standards.
Does Prudence Lifecare export this intermediate internationally?
Yes, Prudence Lifecare exports its API and intermediates portfolio to Asia, Europe, Africa and the Middle East.
Can Prudence Lifecare provide a Certificate of Analysis (CoA) for this intermediate?
Yes, a Certificate of Analysis is available on request — contact our export sales team.
How can I request a quote or technical documentation?
Use the "Request a quote" button on this page or visit our Contacts page.
Need pricing, a Certificate of Analysis, or technical documentation for this intermediate?
Contact our export sales team