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3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate Manufacturer | Prudence Lifecare
Home/ Products/ Intermediates/ 3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate

Prudence Lifecare Pvt. Ltd.

3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate

Manufactured and supplied from our WHO-GMP, GLP and ISO 9001:2015 certified facility in Ankleshwar, Gujarat, India. Available as the racemic aminopropyl- indoline (CAS 1338365-54-0) and its (S)-enantiomer (CAS 1201180-97-3) — both related to the chiral resolution step used to manufacture the (R)-isomer that goes into Silodosin.

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3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate chemical structure
C22H25N3O2
CAS (racemic)
1338365-54-0
CAS (S)-isomer
1201180-97-3
Molecular Weight
363.45 g/mol
Product Type
API Intermediate
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What is this intermediate?

3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate is the aminopropyl-indoline building block used industry-wide in Silodosin synthesis. Only the (R)-configured enantiomer (CAS 239463-72-0 — see our separate page for that grade) carries forward into the finished Silodosin API; this racemic starting material (CAS 1338365-54-0) and the (S)-enantiomer (CAS 1201180-97-3) recovered during chiral resolution are related forms in the same synthesis route. Prudence Lifecare's material is manufactured under the same quality systems that govern our full API and intermediates portfolio.

Application

  • Silodosin synthesis — racemic starting material
  • Chiral resolution intermediate
  • Custom synthesis & CDMO supply
  • Pharmaceutical research & QC reference

Chemical & technical data

Full verified identifiers for both forms of this intermediate, cross-checked against supplier reference data.

3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate — verified chemical identifiers by form
FieldRacemic(S)-Isomer
CAS Number1338365-54-01201180-97-3
Systematic Name5-(2-Aminopropyl)-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile5-[(2S)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile
Molecular FormulaC22H25N3O2C22H25N3O2
Molecular Weight363.45 g/mol363.45 g/mol

Related grade: the (R)-enantiomer used directly in Silodosin manufacturing is CAS 239463-72-0 — see our dedicated page for that identifier and its InChIKey. Specification, purity grade, packaging and Certificate of Analysis details available on request.

Manufacturing & supply

Prudence Lifecare Pvt. Ltd., Unit-II of Prudence Pharma Chem (established 2003), is a WHO, GMP, GLP and ISO 9001:2015 certified Active Pharmaceutical Ingredient and intermediates manufacturer based in GIDC Ankleshwar, Gujarat, India. This intermediate is manufactured under the same quality systems that govern our full API and intermediates portfolio, supplying formulation companies, API manufacturers and contract manufacturers across India and exporting to Asia, Europe, Africa and the Middle East.

Quality, certifications & documentation

  • WHO-GMP, GLP, ISO 9001:2015 and ISO 14001 certified facility
  • Certificate of Analysis (CoA) available on request for either grade
  • Custom purity/particle-size specifications available on request

Why choose Prudence Lifecare

  • WHO, GMP, GLP and ISO-certified facility in Ankleshwar, Gujarat, India
  • In-house manufacture of the (R)-isomer and the finished Silodosin API
  • Export experience across Asia, Europe, Africa and the Middle East
  • Custom synthesis and contract manufacturing (CDMO) capability

Frequently asked questions

What is 3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate used for?

It is a Silodosin-related aminopropyl-indoline intermediate, supplied as the racemic starting material and/or the (S)-enantiomer recovered during chiral resolution of the route.

What is the CAS number of the racemic form?

1338365-54-0.

What is the CAS number of the (S)-isomer?

1201180-97-3.

What is the molecular formula and weight?

C22H25N3O2, 363.45 g/mol — the same for the racemic material, the (S)-isomer, and the (R)-isomer, since stereoisomers share molecular formula and weight.

Which isomer is actually used to make Silodosin?

Only the (R)-configured enantiomer, CAS 239463-72-0, carries forward into finished Silodosin.

Does Prudence Lifecare manufacture the (R)-isomer as well?

Yes — see our dedicated page for (R)-3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate, CAS 239463-72-0.

Does Prudence Lifecare also manufacture the finished Silodosin API?

Yes, Prudence Lifecare manufactures Silodosin (CAS 160970-54-7) to IP and IHS standards.

Who manufactures this intermediate in India?

Prudence Lifecare Pvt. Ltd. manufactures this intermediate at its WHO-GMP certified facility in Ankleshwar, Gujarat, India.

Does Prudence Lifecare export this intermediate internationally?

Yes, Prudence Lifecare exports its API and intermediates portfolio to Asia, Europe, Africa and the Middle East.

How can I request a quote or technical documentation?

Use the "Request a quote" button on this page or visit our Contacts page.

Need pricing, a Certificate of Analysis, or technical documentation for this intermediate?

Contact our export sales team

Get in Touch

CONTACT US
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