Prudence Lifecare Pvt. Ltd.
Silodosin
Manufactured and supplied from our WHO-GMP, GLP and ISO 9001:2015 certified facility in Ankleshwar, Gujarat, India. Silodosin is a highly selective α1A- adrenoceptor antagonist used in the symptomatic treatment of benign prostatic hyperplasia (BPH).
- CAS Number
- 160970-54-7
- PubChem CID
- 5312125
- Molecular Weight
- 495.53 g/mol
- Pharmacopoeia
- IP / IHS
What is Silodosin?
Silodosin is a highly uroselective α1A-adrenoceptor antagonist used for the symptomatic treatment of benign prostatic hyperplasia (BPH). It shows very high affinity for the α1A receptor subtype relative to α1B and α1D, which is associated with a low incidence of orthostatic hypotension compared to other alpha blockers. Prudence Lifecare's Silodosin is manufactured to IP and IHS standards, and Prudence's own intermediates range includes both major building blocks used to construct the molecule — manufactured in-house.
Applications & industries served
- Benign prostatic hyperplasia (BPH) formulations
- Alpha-1A adrenoceptor antagonist products
- Generic & contract (CDMO) manufacturing
- Pharmaceutical research & QC reference
Chemical & technical data
Full verified identifiers for Silodosin, cross-checked against PubChem and supplier reference data.
| Product Name | Silodosin |
|---|---|
| CAS Number | 160970-54-7 |
| PubChem CID | 5312125 |
| Molecular Formula | C25H32F3N3O4 |
| Molecular Weight | 495.53 g/mol |
| IUPAC Name | 1-(3-hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]indoline-7-carboxamide |
| InChIKey | PNCPYILNMDWPEY-QGZVFWFLSA-N |
| Pharmacopoeia Standard | IP / IHS |
| Classification | Selective α1A-adrenoceptor antagonist (indolecarboxamide) |
Chemical identity data sourced and cross-verified via PubChem (CID 5312125). Specification, purity grade, packaging and Certificate of Analysis details available on request.
Manufacturing & supply
Prudence Lifecare Pvt. Ltd., Unit-II of Prudence Pharma Chem (established 2003), is a WHO, GMP, GLP and ISO 9001:2015 certified Active Pharmaceutical Ingredient manufacturer based in GIDC Ankleshwar, Gujarat, India. Silodosin is manufactured under the same quality systems that govern our full API and intermediates portfolio, supplying formulation companies and generic manufacturers across India and exporting to Asia, Europe, Africa and the Middle East.
Quality, certifications & documentation
- WHO-GMP, GLP, ISO 9001:2015 and ISO 14001 certified facility
- Manufactured to IP / IHS standards
- Certificate of Analysis (CoA) available on request
- DMF/CEP documentation status — contact our export sales team to confirm current filing status for this product
Why choose Prudence Lifecare
- WHO, GMP, GLP and ISO-certified facility in Ankleshwar, Gujarat, India
- IP / IHS grade Silodosin
- In-house manufacture of both major Silodosin synthesis intermediates
- Export experience across Asia, Europe, Africa and the Middle East
- Custom synthesis and contract manufacturing (CDMO) capability
Frequently asked questions
What is Silodosin?
Silodosin is a highly selective α1A-adrenoceptor antagonist API used for the symptomatic treatment of benign prostatic hyperplasia (BPH).
What is the CAS number of Silodosin?
160970-54-7.
What is the molecular formula of Silodosin?
C25H32F3N3O4.
What is the molecular weight of Silodosin?
495.53 g/mol.
Which pharmacopoeia standards does Prudence Lifecare's Silodosin meet?
IP and IHS.
Who manufactures Silodosin in India?
Prudence Lifecare Pvt. Ltd. manufactures Silodosin at its WHO-GMP certified facility in Ankleshwar, Gujarat, India.
Is Silodosin available from Gujarat or Ankleshwar?
Yes — Prudence Lifecare's manufacturing facility is located in GIDC Ankleshwar, Gujarat, India.
Does Prudence Lifecare export Silodosin internationally?
Yes, Prudence Lifecare exports its API and intermediates portfolio, including Silodosin, to Asia, Europe, Africa and the Middle East.
What is the PubChem CID of Silodosin?
5312125.
What intermediates does Prudence Lifecare manufacture for Silodosin?
Prudence Lifecare manufactures (R)-3-(7-Cyano-5-(2-Aminopropyl)Indolin-1-yl)Propyl Benzoate and 2-(2-(2,2,2-Trifluoroethoxy)Phenoxy)Ethyl Methanesulfonate — the two building blocks that couple together to form Silodosin's core.
What is the general mechanism of action of Silodosin?
Silodosin selectively blocks α1A-adrenoceptors in the prostate and bladder neck, relaxing smooth muscle and improving urinary flow, with minimal effect on cardiovascular α1B receptors.
Is Silodosin manufactured under GMP conditions at Prudence Lifecare?
Yes — Prudence Lifecare's facility is WHO, GMP, GLP and ISO 9001:2015 certified.
Can Prudence Lifecare provide a Certificate of Analysis (CoA) for Silodosin?
Yes, a Certificate of Analysis is available on request — contact our export sales team.
Does Prudence Lifecare offer DMF/CEP documentation for Silodosin?
Contact our export sales team to confirm current DMF/CEP filing status for this product.
How can I request a quote or technical documentation for Silodosin?
Use the "Request a quote" button on this page or visit our Contacts page.
Need pricing, a Certificate of Analysis, or DMF/CEP documentation for Silodosin?
Contact our export sales team