Prudence Lifecare Pvt. Ltd.
(S)-2-(Oxiran-2-ylmethyl)Isoindoline-1,3-dione [(S)-Glycidyl Phthalimide]
Manufactured and supplied from our WHO-GMP, GLP and ISO 9001:2015 certified facility in Ankleshwar, Gujarat, India. A USP reference-listed chiral building block used to construct Rivaroxaban's oxazolidinone ring with the required (S)-stereochemistry.
- CAS Number
- 161596-47-0
- PubChem CID
- 719412
- Molecular Weight
- 203.19 g/mol
- Product Type
- API Intermediate
What is (S)-Glycidyl Phthalimide?
(S)-2-(Oxiran-2-ylmethyl)Isoindoline-1,3-dione — (S)-Glycidyl Phthalimide — is a chiral epoxide-phthalimide building block listed as a USP reference substance. Its reactive (S)-configured epoxide ring undergoes nucleophilic ring-opening to build the chiral oxazolidinone core of Rivaroxaban with the correct stereochemistry. Prudence Lifecare also manufactures the other two major Rivaroxaban building blocks — 5-Chlorothiophene-2-Carboxylic Acid and 4-(4-Aminophenyl)Morpholin-3-One — alongside the finished Rivaroxaban API.
(S)-Glycidyl Phthalimide – chemical name, synonyms & CAS number
(S)-Glycidyl Phthalimide (CAS 161596-47-0) is listed and searched under several names. Any of the identifiers below can be used when you send an enquiry to Prudence LifeCare.
- Product name: (S)-2-(Oxiran-2-ylmethyl)Isoindoline-1,3-dione [(S)-Glycidyl Phthalimide]
- Chemical name (IUPAC): 2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione
- Also known as: (S)-N-Glycidylphthalimide; (S)-N-(2,3-Epoxypropyl)phthalimide; (S)-2-(Oxiran-2-ylmethyl)Isoindoline-1,3-dione
- CAS number: 161596-47-0
- Molecular formula / weight: C11H9NO3 / 203.19 g/mol
- Used in the synthesis of: Rivaroxaban (CAS 366789-02-8)
Application
- Rivaroxaban synthesis — chiral oxazolidinone building block
- Anticoagulant API manufacturing
- Custom synthesis & CDMO supply
- Pharmaceutical research & QC reference
Chemical & technical data
Full verified identifiers for (S)-Glycidyl Phthalimide, cross-checked against PubChem and the NIH/NCATS reference substance database.
| Product Name | (S)-2-(Oxiran-2-ylmethyl)Isoindoline-1,3-dione [(S)-Glycidyl Phthalimide] |
|---|---|
| CAS Number | 161596-47-0 |
| PubChem CID | 719412 |
| Molecular Formula | C11H9NO3 |
| Molecular Weight | 203.19 g/mol |
| Melting Point | 101–104 °C |
| IUPAC Name | 2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione |
| InChIKey | DUILGEYLVHGSEE-ZETCQYMHSA-N |
| USP Designation | (S)-Glycidyl Phthalimide [USP-RS] |
| Downstream API | Rivaroxaban (CAS 366789-02-8) |
Chemical identity data sourced and cross-verified via PubChem (CID 719412) and the NIH/NCATS Inxight Drugs reference substance database (UNII 9GA7C6L4S5). Specification, purity grade, packaging and Certificate of Analysis details available on request.
Manufacturing & supply
Prudence Lifecare Pvt. Ltd., Unit-II of Prudence Pharma Chem (established 2003), is a WHO, GMP, GLP and ISO 9001:2015 certified Active Pharmaceutical Ingredient and intermediates manufacturer based in GIDC Ankleshwar, Gujarat, India. (S)-Glycidyl Phthalimide is manufactured under the same quality systems that govern our full API and intermediates portfolio, supplying formulation companies, API manufacturers and contract manufacturers across India and exporting to Asia, Europe, Africa and the Middle East.
Quality, certifications & documentation
- WHO-GMP, GLP, ISO 9001:2015 and ISO 14001 certified facility
- Certificate of Analysis (CoA) available on request
- Custom purity/particle-size specifications available on request
Why choose Prudence Lifecare
- WHO, GMP, GLP and ISO-certified facility in Ankleshwar, Gujarat, India
- In-house manufacture of all three major Rivaroxaban synthesis intermediates
- Also the manufacturer of the finished Rivaroxaban API
- Export experience across Asia, Europe, Africa and the Middle East
- Custom synthesis and contract manufacturing (CDMO) capability
Frequently asked questions
What is (S)-Glycidyl Phthalimide used for?
It is used to construct Rivaroxaban's chiral oxazolidinone ring, supplying the required (S)-stereochemistry.
What is the CAS number of (S)-Glycidyl Phthalimide?
161596-47-0.
What is the molecular formula of (S)-Glycidyl Phthalimide?
C11H9NO3.
What is the molecular weight of (S)-Glycidyl Phthalimide?
203.19 g/mol.
What is the PubChem CID of (S)-Glycidyl Phthalimide?
719412.
What is the full chemical name of (S)-Glycidyl Phthalimide?
The chemical (IUPAC) name of (S)-Glycidyl Phthalimide is 2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione. It is also known as (S)-N-Glycidylphthalimide; (S)-N-(2,3-Epoxypropyl)phthalimide; (S)-2-(Oxiran-2-ylmethyl)Isoindoline-1,3-dione.
What is the (S)-Glycidyl Phthalimide price in India?
The price of (S)-Glycidyl Phthalimide depends on order quantity, grade, documentation requirements and destination. Share your requirement with the Prudence LifeCare sales team to receive a current quotation.
Is (S)-Glycidyl Phthalimide an official USP reference substance?
Yes — it is listed as (S)-Glycidyl Phthalimide [USP-RS] in the reference substance database.
Who manufactures (S)-Glycidyl Phthalimide in India?
Prudence Lifecare Pvt. Ltd. manufactures (S)-Glycidyl Phthalimide at its WHO-GMP certified facility in Ankleshwar, Gujarat, India.
What other Rivaroxaban intermediates does Prudence Lifecare manufacture?
Prudence Lifecare also manufactures 5-Chlorothiophene-2-Carboxylic Acid (CAS 24065-33-6) and 4-(4-Aminophenyl)Morpholin-3-One (CAS 438056-69-0), the other two major Rivaroxaban building blocks.
Does Prudence Lifecare also manufacture the finished Rivaroxaban API?
Yes, Prudence Lifecare manufactures Rivaroxaban (CAS 366789-02-8) to IHS, BP, EP and USP standards.
How can I request a quote or technical documentation?
Use the "Request a quote" button on this page or visit our Contacts page.
Which product has CAS number 161596-47-0?
CAS number 161596-47-0 identifies (S)-2-(Oxiran-2-ylmethyl)Isoindoline-1,3-dione. Prudence LifeCare manufactures and supplies (S)-Glycidyl Phthalimide (CAS 161596-47-0) from Ankleshwar, Gujarat, India.
What is the specification of (S)-Glycidyl Phthalimide?
(S)-Glycidyl Phthalimide is supplied with a batch-wise Certificate of Analysis (CoA). Detailed specifications are shared on request.
Need pricing, a Certificate of Analysis, or technical documentation for (S)-Glycidyl Phthalimide?
Contact our export sales team