Prudence Lifecare Pvt. Ltd.
S-Amlodipine Base / Leva Amlodipine Base
Manufactured and supplied from our WHO-GMP, GLP and ISO 9001:2015 certified facility in Ankleshwar, Gujarat, India. S-Amlodipine Base is the enantiopure free-base form of amlodipine — the pharmacologically active (S)-enantiomer — used to manufacture S-Amlodipine Besylate and S-Amlodipine Maleate.
- CAS Number
- 103129-82-4
- Molecular Weight
- 408.88 g/mol
- Product Type
- API Intermediate
- Used to Manufacture
- S-Amlodipine salts
What is S-Amlodipine Base?
S-Amlodipine Base — also known as Levamlodipine or Leva Amlodipine Base — is the single, enantiopure (S)-form of amlodipine free base, and the pharmacologically active moiety of the racemic drug. It is the common precursor to Prudence Lifecare's enantiopure amlodipine salts: S-Amlodipine Besylate (Levamlodipine Besylate, CAS 150566-71-5) and S-Amlodipine Maleate (Levamlodipine Maleate, CAS 135969-53-8), combining with the respective counter-ion to form each finished salt.
Application
- S-Amlodipine salt manufacturing — enantiopure free-base precursor
- Calcium channel blocker API manufacturing
- Custom synthesis & CDMO supply
- Pharmaceutical research & QC reference
Chemical & technical data
Full verified identifiers for S-Amlodipine Base, cross-checked against RCSB/NCATS reference data and supplier records.
| Product Name | S-Amlodipine Base (Leva Amlodipine Base) |
|---|---|
| CAS Number | 103129-82-4 |
| Molecular Formula | C20H25ClN2O5 |
| Molecular Weight | 408.88 g/mol |
| IUPAC Name | 3-O-ethyl 5-O-methyl (4S)-2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate |
| InChIKey | HTIQEAQVCYTUBX-KRWDZBQOSA-N |
| Also Known As | Levamlodipine, Levoamlodipine, l-Amlodipine, (S)-Amlodipine |
| Downstream Products | S-Amlodipine Besylate (CAS 150566-71-5), S-Amlodipine Maleate (CAS 135969-53-8) |
Chemical identity data sourced and cross-verified via the RCSB Protein Data Bank ligand record (6UB) and the NIH/NCATS Inxight Drugs reference substance database (UNII 0P6NLP6806). Specification, purity grade, packaging and Certificate of Analysis details available on request.
Manufacturing & supply
Prudence Lifecare Pvt. Ltd., Unit-II of Prudence Pharma Chem (established 2003), is a WHO, GMP, GLP and ISO 9001:2015 certified Active Pharmaceutical Ingredient and intermediates manufacturer based in GIDC Ankleshwar, Gujarat, India. S-Amlodipine Base is manufactured under the same quality systems that govern our full API and intermediates portfolio, supplying formulation companies, API manufacturers and contract manufacturers across India and exporting to Asia, Europe, Africa and the Middle East.
Quality, certifications & documentation
- WHO-GMP, GLP, ISO 9001:2015 and ISO 14001 certified facility
- Certificate of Analysis (CoA) available on request
- Custom purity/particle-size specifications available on request
Why choose Prudence Lifecare
- WHO, GMP, GLP and ISO-certified facility in Ankleshwar, Gujarat, India
- In-house manufacture of the full enantiopure S-amlodipine salt family from this common precursor
- Export experience across Asia, Europe, Africa and the Middle East
- Custom synthesis and contract manufacturing (CDMO) capability
Frequently asked questions
What is S-Amlodipine Base used for?
It is the enantiopure free-base precursor from which S-Amlodipine Besylate and S-Amlodipine Maleate are made.
What is the CAS number of S-Amlodipine Base?
103129-82-4.
What is the molecular formula of S-Amlodipine Base?
C20H25ClN2O5 — the same formula as racemic Amlodipine Base, since it is the isolated (S)-enantiomer.
What is the molecular weight of S-Amlodipine Base?
408.88 g/mol.
Is S-Amlodipine Base the same as Levamlodipine?
Yes — S-Amlodipine, Levamlodipine, Levoamlodipine and l-Amlodipine all refer to the same enantiopure (S)-form.
Who manufactures S-Amlodipine Base in India?
Prudence Lifecare Pvt. Ltd. manufactures S-Amlodipine Base at its WHO-GMP certified facility in Ankleshwar, Gujarat, India.
What S-amlodipine salts does Prudence Lifecare make from this precursor?
S-Amlodipine Besylate (Levamlodipine Besylate) and S-Amlodipine Maleate (Levamlodipine Maleate).
How does S-Amlodipine Base differ from racemic Amlodipine Base?
Racemic Amlodipine Base contains both R- and S-enantiomers, but only the S-enantiomer is pharmacologically active. S-Amlodipine Base isolates that active form.
Does Prudence Lifecare export S-Amlodipine Base internationally?
Yes, Prudence Lifecare exports its API and intermediates portfolio to Asia, Europe, Africa and the Middle East.
How can I request a quote or technical documentation?
Use the "Request a quote" button on this page or visit our Contacts page.
Need pricing, a Certificate of Analysis, or technical documentation for S-Amlodipine Base?
Contact our export sales team