Prudence Lifecare Pvt. Ltd.
1-(6-Methylpyridin-3-yl)-2-[4-(Methylsulfonyl)Phenyl]Ethanone [Ketosulfone]
Manufactured and supplied from our WHO-GMP, GLP and ISO 9001:2015 certified facility in Ankleshwar, Gujarat, India. Officially designated Etoricoxib Impurity D, Ketosulfone is used together with CDT-Salt to build Etoricoxib's pyridine core.
- CAS Number
- 221615-75-4
- PubChem CID
- 9925991
- Molecular Weight
- 289.35 g/mol
- Product Type
- API Intermediate
What is Ketosulfone?
Ketosulfone — 1-(6-Methylpyridin-3-yl)-2-[4-(Methylsulfonyl)Phenyl]Ethanone — is a key methylsulfonylphenyl-pyridine building block, officially designated Etoricoxib Impurity D by regulatory reference-standard databases. Documented in process patents (e.g. US 9,085,532) as prepared via Pd-catalysed alpha-arylation, it is used together with CDT-Salt (2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate) to build Etoricoxib's pyridine core through cyclization. Prudence Lifecare also manufactures CDT-Salt (CAS 249561-98-6) and the finished Etoricoxib API.
Application
- Etoricoxib synthesis — pyridine-ring building block
- COX-2 inhibitor API manufacturing
- Custom synthesis & CDMO supply
- Pharmaceutical research & QC reference
Chemical & technical data
Full verified identifiers for Ketosulfone, cross-checked against PubChem and the NIH/NCATS reference substance database.
| Product Name | 1-(6-Methylpyridin-3-yl)-2-[4-(Methylsulfonyl)Phenyl]Ethanone [Ketosulfone] |
|---|---|
| CAS Number | 221615-75-4 |
| PubChem CID | 9925991 |
| Molecular Formula | C15H15NO3S |
| Molecular Weight | 289.35 g/mol |
| IUPAC Name | 1-(6-methylpyridin-3-yl)-2-(4-methylsulfonylphenyl)ethanone |
| InChIKey | YBFHILNBYXCJKD-UHFFFAOYSA-N |
| USP/Reference Designation | Etoricoxib Impurity D |
| Downstream API | Etoricoxib (CAS 202409-33-4) |
Chemical identity data sourced and cross-verified via PubChem (CID 9925991) and the NIH/NCATS Inxight Drugs reference substance database (UNII RCYJMCPV68). Specification, purity grade, packaging and Certificate of Analysis details available on request.
Manufacturing & supply
Prudence Lifecare Pvt. Ltd., Unit-II of Prudence Pharma Chem (established 2003), is a WHO, GMP, GLP and ISO 9001:2015 certified Active Pharmaceutical Ingredient and intermediates manufacturer based in GIDC Ankleshwar, Gujarat, India. Ketosulfone is manufactured under the same quality systems that govern our full API and intermediates portfolio, supplying formulation companies, API manufacturers and contract manufacturers across India and exporting to Asia, Europe, Africa and the Middle East.
Quality, certifications & documentation
- WHO-GMP, GLP, ISO 9001:2015 and ISO 14001 certified facility
- Certificate of Analysis (CoA) available on request
- Custom purity/particle-size specifications available on request
Why choose Prudence Lifecare
- WHO, GMP, GLP and ISO-certified facility in Ankleshwar, Gujarat, India
- In-house manufacture of both major Etoricoxib synthesis intermediates
- Also the manufacturer of the finished Etoricoxib API
- Export experience across Asia, Europe, Africa and the Middle East
- Custom synthesis and contract manufacturing (CDMO) capability
Frequently asked questions
What is Ketosulfone used for?
It is used together with CDT-Salt to build Etoricoxib's pyridine core via cyclization.
What is the CAS number of Ketosulfone?
221615-75-4.
What is the molecular formula of Ketosulfone?
C15H15NO3S.
What is the molecular weight of Ketosulfone?
289.35 g/mol.
What is the PubChem CID of Ketosulfone?
9925991.
Is Ketosulfone an official reference substance?
Yes — it is designated Etoricoxib Impurity D in reference-standard databases.
Who manufactures Ketosulfone in India?
Prudence Lifecare Pvt. Ltd. manufactures Ketosulfone at its WHO-GMP certified facility in Ankleshwar, Gujarat, India.
What other Etoricoxib intermediate does Prudence Lifecare manufacture?
Prudence Lifecare also manufactures CDT-Salt (2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate, CAS 249561-98-6), the other building block used with Ketosulfone to form Etoricoxib.
Does Prudence Lifecare also manufacture the finished Etoricoxib API?
Yes, Prudence Lifecare manufactures Etoricoxib (CAS 202409-33-4) to IP and IHS standards.
How can I request a quote or technical documentation?
Use the "Request a quote" button on this page or visit our Contacts page.
Need pricing, a Certificate of Analysis, or technical documentation for Ketosulfone?
Contact our export sales team