Prudence Lifecare Pvt. Ltd.
Ethyl 2-(3-Formyl-4-Isobutoxyphenyl)-4-Methyl-1,3-Thiazole-5-Carboxylate [Febuxostat Impurity 2]
Manufactured and supplied from our WHO-GMP, GLP and ISO 9001:2015 certified facility in Ankleshwar, Gujarat, India. This is the upstream formyl (aldehyde) precursor in Febuxostat synthesis, converted to the cyano intermediate before final hydrolysis to the finished API.
- CAS Number
- 161798-03-4
- Molecular Weight
- 347.43 g/mol
- Product Type
- API Intermediate
- Used to Manufacture
- Febuxostat
What is this intermediate?
Ethyl 2-(3-Formyl-4-Isobutoxyphenyl)-4-Methyl-1,3-Thiazole-5-Carboxylate — widely documented by reference-standard suppliers as "Febuxostat Impurity 2" or "Febuxostat Impurity G" — is the upstream aldehyde (formyl) precursor in Febuxostat synthesis. It is converted to the corresponding nitrile (Ethyl 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methyl-1,3-Thiazole-5-Carboxylate, CAS 160844-75-7 — also manufactured by Prudence Lifecare) via oximation and dehydration, before final hydrolysis to Febuxostat. Prudence Lifecare also manufactures the finished Febuxostat API.
Application
- Febuxostat synthesis — upstream formyl intermediate
- Xanthine oxidase inhibitor API manufacturing
- Custom synthesis & CDMO supply
- Pharmaceutical research & QC reference
Chemical & technical data
Full verified identifiers for this intermediate, cross-checked against supplier reference data.
| Product Name | Ethyl 2-(3-Formyl-4-Isobutoxyphenyl)-4-Methyl-1,3-Thiazole-5-Carboxylate |
|---|---|
| CAS Number | 161798-03-4 |
| Molecular Formula | C18H21NO4S |
| Molecular Weight | 347.43 g/mol |
| Melting Point | 162–165 °C |
| IUPAC Name | ethyl 2-[3-formyl-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylate |
| InChIKey | AIQMFFCWDAIGNV-UHFFFAOYSA-N |
| Product Type | Active Pharmaceutical Ingredient (API) intermediate |
| Downstream API | Febuxostat (CAS 144060-53-7) |
Also listed industry-wide as Febuxostat Impurity 2 / Febuxostat Impurity G. Specification, purity grade, packaging and Certificate of Analysis details available on request.
Manufacturing & supply
Prudence Lifecare Pvt. Ltd., Unit-II of Prudence Pharma Chem (established 2003), is a WHO, GMP, GLP and ISO 9001:2015 certified Active Pharmaceutical Ingredient and intermediates manufacturer based in GIDC Ankleshwar, Gujarat, India. This intermediate is manufactured under the same quality systems that govern our full API and intermediates portfolio, supplying formulation companies, API manufacturers and contract manufacturers across India and exporting to Asia, Europe, Africa and the Middle East.
Quality, certifications & documentation
- WHO-GMP, GLP, ISO 9001:2015 and ISO 14001 certified facility
- Certificate of Analysis (CoA) available on request
- Custom purity/particle-size specifications available on request
Why choose Prudence Lifecare
- WHO, GMP, GLP and ISO-certified facility in Ankleshwar, Gujarat, India
- In-house manufacture of both major Febuxostat synthesis intermediates
- Also the manufacturer of the finished Febuxostat API
- Export experience across Asia, Europe, Africa and the Middle East
- Custom synthesis and contract manufacturing (CDMO) capability
Frequently asked questions
What is this intermediate used for?
It is the upstream formyl (aldehyde) precursor in Febuxostat synthesis, converted to the cyano intermediate before final hydrolysis to the finished API.
What is the CAS number of this intermediate?
161798-03-4.
What is the molecular formula of this intermediate?
C18H21NO4S.
What is the molecular weight of this intermediate?
347.43 g/mol.
Is this intermediate the same as "Febuxostat Impurity 2"?
Yes — it is widely referred to industry-wide as Febuxostat Impurity 2 or Febuxostat Impurity G.
Who manufactures this intermediate in India?
Prudence Lifecare Pvt. Ltd. manufactures this intermediate at its WHO-GMP certified facility in Ankleshwar, Gujarat, India.
What other Febuxostat intermediate does Prudence Lifecare manufacture?
Prudence Lifecare also manufactures Ethyl 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methyl-1,3-Thiazole-5-Carboxylate (CAS 160844-75-7), the direct ethyl-ester precursor of Febuxostat.
Does Prudence Lifecare also manufacture the finished Febuxostat API?
Yes, Prudence Lifecare manufactures Febuxostat (CAS 144060-53-7) to IHS standard.
Does Prudence Lifecare export this intermediate internationally?
Yes, Prudence Lifecare exports its API and intermediates portfolio to Asia, Europe, Africa and the Middle East.
How can I request a quote or technical documentation?
Use the "Request a quote" button on this page or visit our Contacts page.
Need pricing, a Certificate of Analysis, or technical documentation for this intermediate?
Contact our export sales team