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2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One [HBO] Manufacturer | Prudence Lifecare
Home/ Products/ Intermediates/ 2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One

Prudence Lifecare Pvt. Ltd.

2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One [HBO]

Manufactured and supplied from our WHO-GMP, GLP and ISO 9001:2015 certified facility in Ankleshwar, Gujarat, India. This benzoxazinone building block, known in the industry as HBO, is widely documented as a key synthetic intermediate for Deferasirox, an iron-chelating agent.

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2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One [HBO] (CAS 1218-69-5) chemical structure
C14H9NO3
CAS Number
1218-69-5
Molecular Weight
239.23 g/mol
Product Type
API Intermediate
Industry Use
Deferasirox synthesis
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What is HBO?

2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One — commonly abbreviated HBO — is a benzoxazinone formed by cyclodehydration of salicylic acid and salicylamide. It is widely documented across patent literature and reference-standard suppliers as a key intermediate in the synthesis of Deferasirox, where it reacts to build the bis(2-hydroxyphenyl)-triazole core of the finished drug substance. Prudence Lifecare's HBO is manufactured under the same WHO-GMP quality systems that govern our full API and intermediates portfolio.

HBO – chemical name, synonyms & CAS number

HBO (CAS 1218-69-5) is listed and searched under several names. Any of the identifiers below can be used when you send an enquiry to Prudence LifeCare.

  • Product name: 2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One [HBO]
  • Chemical name (IUPAC): 2-(2-hydroxyphenyl)-4H-benzo[e][1,3]oxazin-4-one
  • Also known as: 2-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one; 2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One
  • CAS number: 1218-69-5
  • Molecular formula / weight: C14H9NO3 / 239.23 g/mol
  • Used in the synthesis of: Deferasirox

Application

  • Deferasirox synthesis intermediate
  • Iron-chelating agent API manufacturing
  • Custom synthesis & CDMO supply
  • Pharmaceutical research & QC reference

Chemical & technical data

Full verified identifiers for HBO, cross-checked against supplier reference data.

2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One [HBO] verified chemical identifiers
Product Name2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One [HBO]
CAS Number1218-69-5
Molecular FormulaC14H9NO3
Molecular Weight239.23 g/mol
Melting Point204–208 °C
Systematic Name2-(2-hydroxyphenyl)-4H-benzo[e][1,3]oxazin-4-one
InChIKey NSWIROGSZPXREF-UHFFFAOYSA-N
Product TypeActive Pharmaceutical Ingredient (API) intermediate
Industry Downstream UseDeferasirox

Specification, purity grade, packaging and Certificate of Analysis details available on request.

Manufacturing & supply

Prudence Lifecare Pvt. Ltd., Unit-II of Prudence Pharma Chem (established 2003), is a WHO, GMP, GLP and ISO 9001:2015 certified Active Pharmaceutical Ingredient and intermediates manufacturer based in GIDC Ankleshwar, Gujarat, India. HBO is manufactured under the same quality systems that govern our full API and intermediates portfolio, supplying formulation companies, API manufacturers and contract manufacturers across India and exporting to Asia, Europe, Africa and the Middle East.

Quality, certifications & documentation

  • WHO-GMP, GLP, ISO 9001:2015 and ISO 14001 certified facility
  • Certificate of Analysis (CoA) available on request
  • Custom purity/particle-size specifications available on request

Why choose Prudence Lifecare

  • WHO, GMP, GLP and ISO-certified facility in Ankleshwar, Gujarat, India
  • Broad API and intermediates portfolio manufactured under one quality system
  • Export experience across Asia, Europe, Africa and the Middle East
  • Custom synthesis and contract manufacturing (CDMO) capability

Related products

Related intermediates

  • 4-Hydrazinobenzoic Acid [4-HBA]

Browse the range

  • All APIs
  • All pharmaceutical intermediates

Frequently asked questions

What is HBO used for?

HBO (2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One) is documented industry-wide as a key synthetic intermediate for Deferasirox, an iron-chelating agent.

What is the CAS number of HBO?

1218-69-5.

What is the molecular formula of HBO?

C14H9NO3.

What is the molecular weight of HBO?

239.23 g/mol.

Who manufactures HBO in India?

Prudence Lifecare Pvt. Ltd. manufactures HBO at its WHO-GMP certified facility in Ankleshwar, Gujarat, India.

What is the full chemical name of HBO?

The chemical (IUPAC) name of HBO is 2-(2-hydroxyphenyl)-4H-benzo[e][1,3]oxazin-4-one. It is also known as 2-(2-Hydroxyphenyl)-4H-1,3-benzoxazin-4-one; 2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One.

What is the HBO price in India?

The price of HBO depends on order quantity, grade, documentation requirements and destination. Share your requirement with the Prudence LifeCare sales team to receive a current quotation.

How is HBO made?

HBO is formed by the cyclodehydration of salicylic acid and salicylamide.

Does Prudence Lifecare export HBO internationally?

Yes, Prudence Lifecare exports its API and intermediates portfolio to Asia, Europe, Africa and the Middle East.

Can Prudence Lifecare provide a Certificate of Analysis (CoA) for HBO?

Yes, a Certificate of Analysis is available on request — contact our export sales team.

Is HBO manufactured under GMP conditions at Prudence Lifecare?

Yes — Prudence Lifecare's facility is WHO, GMP, GLP and ISO 9001:2015 certified.

How can I request a quote or technical documentation?

Use the "Request a quote" button on this page or visit our Contacts page.

Which product has CAS number 1218-69-5?

CAS number 1218-69-5 identifies 2-(2-Hydroxyphenyl)-4H-1,3-Benzoxazine-4-One. Prudence LifeCare manufactures and supplies HBO (CAS 1218-69-5) from Ankleshwar, Gujarat, India.

What is the specification of HBO?

HBO is supplied with a batch-wise Certificate of Analysis (CoA). Detailed specifications are shared on request.

Need pricing, a Certificate of Analysis, or technical documentation for HBO?

Contact our export sales team

Get in Touch

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