Prudence Lifecare Pvt. Ltd.
Glibenclamide / Glyburide
Manufactured and supplied from our WHO-GMP, GLP and ISO 9001:2015 certified facility in Ankleshwar, Gujarat, India. Glibenclamide (Glyburide) is a second-generation sulfonylurea, an ATP-dependent potassium channel blocker used as an oral antidiabetic agent in type 2 diabetes formulations.
- CAS Number
- 10238-21-8
- PubChem CID
- 3488
- Molecular Weight
- 494.00 g/mol
- Pharmacopoeia
- IP / BP / EP
What is Glibenclamide (Glyburide)?
Glibenclamide — known as Glyburide in the USAN/USP naming convention — is a second-generation sulfonylurea that blocks ATP-dependent potassium (KATP) channels on pancreatic beta cells, stimulating insulin secretion. It is one of the most widely manufactured oral antidiabetic APIs. Prudence Lifecare's Glibenclamide is manufactured to IP, BP and EP pharmacopoeial standards.
Applications & industries served
- Type 2 diabetes formulations
- Oral antidiabetic (sulfonylurea) products
- Fixed-dose combination products (e.g., with metformin)
- Generic & contract (CDMO) manufacturing
- Pharmaceutical research & QC reference
Chemical & technical data
Full verified identifiers for Glibenclamide, cross-checked against PubChem and supplier reference data.
| Product Name | Glibenclamide (Glyburide) |
|---|---|
| CAS Number | 10238-21-8 |
| PubChem CID | 3488 |
| Molecular Formula | C23H28ClN3O5S |
| Molecular Weight | 494.00 g/mol |
| Exact Mass | 493.1438 |
| IUPAC Name | 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide |
| InChIKey | ZNNLBTZKUZBEKO-UHFFFAOYSA-N |
| Pharmacopoeia Standard | IP / BP / EP |
| Classification | Second-generation sulfonylurea (KATP channel blocker) |
Chemical identity data sourced and cross-verified via PubChem (CID 3488). Specification, purity grade, packaging and Certificate of Analysis details available on request.
Manufacturing & supply
Prudence Lifecare Pvt. Ltd., Unit-II of Prudence Pharma Chem (established 2003), is a WHO, GMP, GLP and ISO 9001:2015 certified Active Pharmaceutical Ingredient manufacturer based in GIDC Ankleshwar, Gujarat, India. Glibenclamide is manufactured under the same quality systems that govern our full API and intermediates portfolio, supplying formulation companies and generic manufacturers across India and exporting to Asia, Europe, Africa and the Middle East.
Quality, certifications & documentation
- WHO-GMP, GLP, ISO 9001:2015 and ISO 14001 certified facility
- Manufactured to IP / BP / EP pharmacopoeial standards
- Certificate of Analysis (CoA) available on request
- DMF/CEP documentation status — contact our export sales team to confirm current filing status for this product
Why choose Prudence Lifecare
- WHO, GMP, GLP and ISO-certified facility in Ankleshwar, Gujarat, India
- IP / BP / EP pharmacopoeia-grade Glibenclamide
- Broad API and intermediates portfolio manufactured under one quality system
- Export experience across Asia, Europe, Africa and the Middle East
- Custom synthesis and contract manufacturing (CDMO) capability
Frequently asked questions
What is Glibenclamide?
Glibenclamide, also known as Glyburide, is a second-generation sulfonylurea API that blocks ATP-dependent potassium channels on pancreatic beta cells to stimulate insulin secretion.
Is Glibenclamide the same as Glyburide?
Yes. "Glibenclamide" is the INN/BP/EP name and "Glyburide" is the USAN/USP name for the same substance, CAS 10238-21-8.
What is the CAS number of Glibenclamide?
10238-21-8.
What is the molecular formula of Glibenclamide?
C23H28ClN3O5S.
What is the molecular weight of Glibenclamide?
494.00 g/mol.
Which pharmacopoeia standards does Prudence Lifecare's Glibenclamide meet?
IP, BP and EP.
Who manufactures Glibenclamide in India?
Prudence Lifecare Pvt. Ltd. manufactures Glibenclamide at its WHO-GMP certified facility in Ankleshwar, Gujarat, India.
Is Glibenclamide available from Gujarat or Ankleshwar?
Yes — Prudence Lifecare's manufacturing facility is located in GIDC Ankleshwar, Gujarat, India.
Does Prudence Lifecare export Glibenclamide internationally?
Yes, Prudence Lifecare exports its API and intermediates portfolio, including Glibenclamide, to Asia, Europe, Africa and the Middle East.
What is the PubChem CID of Glibenclamide?
3488.
What is the general mechanism of action of Glibenclamide?
Glibenclamide blocks ATP-dependent potassium (KATP) channels on pancreatic beta cells, depolarizing them and stimulating calcium influx, which triggers insulin release.
Is Glibenclamide manufactured under GMP conditions at Prudence Lifecare?
Yes — Prudence Lifecare's facility is WHO, GMP, GLP and ISO 9001:2015 certified.
Can Prudence Lifecare provide a Certificate of Analysis (CoA) for Glibenclamide?
Yes, a Certificate of Analysis is available on request — contact our export sales team.
Does Prudence Lifecare offer DMF/CEP documentation for Glibenclamide?
Contact our export sales team to confirm current DMF/CEP filing status for this product.
How can I request a quote or technical documentation for Glibenclamide?
Use the "Request a quote" button on this page or visit our Contacts page.
Need pricing, a Certificate of Analysis, or DMF/CEP documentation for Glibenclamide?
Contact our export sales team