Prudence Lifecare Pvt. Ltd.
1-(4-Methylphenyl)-4,4,4-Trifluorobutane-1,3-Dione
Manufactured and supplied from our WHO-GMP, GLP and ISO 9001:2015 certified facility in Ankleshwar, Gujarat, India. This trifluoromethyl diketone is one of the two starting materials used to build Celecoxib's pyrazole core, a selective COX-2 inhibitor NSAID.
- CAS Number
- 720-94-5
- PubChem CID
- 550193
- Molecular Weight
- 230.18 g/mol
- Product Type
- API Intermediate
What is this intermediate?
1-(4-Methylphenyl)-4,4,4-Trifluorobutane-1,3-Dione is a trifluoromethyl-substituted 1,3-diketone, documented in the original Celecoxib medicinal chemistry literature (Penning et al., J. Med. Chem. 1997; Prasit et al., Bioorg. Med. Chem. Lett. 1999) as a key starting material. It undergoes cyclocondensation with 4-Hydrazinobenzenesulfonamide HCl — also manufactured by Prudence Lifecare — to form Celecoxib's pyrazole core directly. Prudence Lifecare also manufactures the finished Celecoxib API.
Trifluoro Butane Dione – chemical name, synonyms & CAS number
Trifluoro Butane Dione (CAS 720-94-5) is listed and searched under several names. Any of the identifiers below can be used when you send an enquiry to Prudence LifeCare.
- Product name: 1-(4-Methylphenyl)-4,4,4-Trifluorobutane-1,3-Dione
- Chemical name (IUPAC): 4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione
- Also known as: 4,4,4-Trifluoro-1-(p-tolyl)butane-1,3-dione; 1-(4-Methylphenyl)-4,4,4-Trifluorobutane-1,3-Dione
- CAS number: 720-94-5
- Molecular formula / weight: C11H9F3O2 / 230.18 g/mol
- Used in the synthesis of: Celecoxib (CAS 169590-42-5)
Application
- Celecoxib synthesis intermediate
- COX-2 inhibitor API manufacturing
- Custom synthesis & CDMO supply
- Pharmaceutical research & QC reference
Chemical & technical data
Full verified identifiers for this intermediate, cross-checked against PubChem and supplier reference data.
| Product Name | 1-(4-Methylphenyl)-4,4,4-Trifluorobutane-1,3-Dione |
|---|---|
| CAS Number | 720-94-5 |
| PubChem CID | 550193 |
| Molecular Formula | C11H9F3O2 |
| Molecular Weight | 230.18 g/mol |
| Melting Point | 44–46 °C |
| IUPAC Name | 4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione |
| InChIKey | WRZMHTIRFOFFPY-UHFFFAOYSA-N |
| Product Type | Active Pharmaceutical Ingredient (API) intermediate |
| Downstream API | Celecoxib (CAS 169590-42-5) |
Chemical identity data sourced and cross-verified via PubChem (CID 550193). Specification, purity grade, packaging and Certificate of Analysis details available on request.
Manufacturing & supply
Prudence Lifecare Pvt. Ltd., Unit-II of Prudence Pharma Chem (established 2003), is a WHO, GMP, GLP and ISO 9001:2015 certified Active Pharmaceutical Ingredient and intermediates manufacturer based in GIDC Ankleshwar, Gujarat, India. This intermediate is manufactured under the same quality systems that govern our full API and intermediates portfolio, supplying formulation companies, API manufacturers and contract manufacturers across India and exporting to Asia, Europe, Africa and the Middle East.
Quality, certifications & documentation
- WHO-GMP, GLP, ISO 9001:2015 and ISO 14001 certified facility
- Certificate of Analysis (CoA) available on request
- Custom purity/particle-size specifications available on request
Why choose Prudence Lifecare
- WHO, GMP, GLP and ISO-certified facility in Ankleshwar, Gujarat, India
- In-house manufacture of both major Celecoxib synthesis intermediates
- Also the manufacturer of the finished Celecoxib API
- Export experience across Asia, Europe, Africa and the Middle East
- Custom synthesis and contract manufacturing (CDMO) capability
Frequently asked questions
What is this intermediate used for?
It undergoes cyclocondensation with 4-Hydrazinobenzenesulfonamide HCl to form Celecoxib's pyrazole core.
What is the CAS number of this intermediate?
720-94-5.
What is the molecular formula of this intermediate?
C11H9F3O2.
What is the molecular weight of this intermediate?
230.18 g/mol.
What is the PubChem CID of this intermediate?
550193.
What is the full chemical name of Trifluoro Butane Dione?
The chemical (IUPAC) name of Trifluoro Butane Dione is 4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione. It is also known as 4,4,4-Trifluoro-1-(p-tolyl)butane-1,3-dione; 1-(4-Methylphenyl)-4,4,4-Trifluorobutane-1,3-Dione.
What is the Trifluoro Butane Dione price in India?
The price of Trifluoro Butane Dione depends on order quantity, grade, documentation requirements and destination. Share your requirement with the Prudence LifeCare sales team to receive a current quotation.
Who manufactures this intermediate in India?
Prudence Lifecare Pvt. Ltd. manufactures this intermediate at its WHO-GMP certified facility in Ankleshwar, Gujarat, India.
What other Celecoxib intermediate does Prudence Lifecare manufacture?
Prudence Lifecare also manufactures 4-Hydrazinobenzenesulfonamide HCl (CAS 17852-52-7), the other starting material used to build Celecoxib.
Does Prudence Lifecare also manufacture the finished Celecoxib API?
Yes, Prudence Lifecare manufactures Celecoxib (CAS 169590-42-5) to IHS, BP, EP and USP standards.
Does Prudence Lifecare export this intermediate internationally?
Yes, Prudence Lifecare exports its API and intermediates portfolio to Asia, Europe, Africa and the Middle East.
How can I request a quote or technical documentation?
Use the "Request a quote" button on this page or visit our Contacts page.
Which product has CAS number 720-94-5?
CAS number 720-94-5 identifies 1-(4-Methylphenyl)-4,4,4-Trifluorobutane-1,3-Dione. Prudence LifeCare manufactures and supplies Trifluoro Butane Dione (CAS 720-94-5) from Ankleshwar, Gujarat, India.
What is the specification of Trifluoro Butane Dione?
Trifluoro Butane Dione is supplied with a batch-wise Certificate of Analysis (CoA). Detailed specifications are shared on request.
Need pricing, a Certificate of Analysis, or technical documentation for this intermediate?
Contact our export sales team